Obesity, Insulin Resistance, and Nocturnal Systolic Blood Pressure

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Obesity, insulin resistance, and nocturnal systolic blood pressure.

An increasing prevalence of obesity is observed in all age and ethnicity groups and is increasingly being recognized as a serious health problem in children and adolescents.1–4 Obesity is associated with a number of metabolic abnormalities, as well as increased risk for cardiovascular disease (CVD).3,4 In this issue of Hypertension, Lurbe et al5 reported a relationship between insulin resistanc...

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Added impact of obesity and insulin resistance in nocturnal blood pressure elevation in children and adolescents.

The aim of the present study was to analyze the relationship between insulin resistance and the ambulatory blood pressure components in obese children and adolescents. Eighty-seven overweight and obese white children and adolescents of both sexes, of European origin from 6 to 18 years of age (mean age: 10.9+/-2.7 years), were selected. Obesity was defined on the basis of a threshold body mass i...

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Insulin and blood pressure in obesity.

To assess factors in overweight persons that account for a tendency toward hypertension, 33 very obese women, 26 to 77 years of age, were studied. Blood pressures in these 33 women varied from low normal to mildly hypertensive. None of them had taken medication for high blood pressure, and none had diabetes mellitus. The effect of independent variables--age, body mass index (weight/height2), fa...

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Cardiovascular autonomic dysfunction as a link between insulin resistance and nocturnal blood pressure elevation.

Cardiovascular Autonomic Dysfunction as a Link Between Insulin Resistance and Nocturnal Blood Pressure Elevation To the Editor: I read with interest the article by Lurbe et al1 on the relationship between insulin resistance and the ambulatory blood pressure components in obese children and adolescents. The authors have observed that nocturnal systolic blood pressure and heart rate were signific...

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Association of insulin resistance with salt sensitivity and nocturnal fall of blood pressure.

Insulin resistance was demonstrated in hypertensive patients and in salt-sensitive subjects. It was recently reported that the salt-sensitive state was related to a reduced fall in blood pressure during the night in essential hypertension. In the present study, the relationship among insulin sensitivity, blood pressure response to salt intake, and nocturnal fall in blood pressure was examined i...

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ژورنال

عنوان ژورنال: Hypertension

سال: 2008

ISSN: 0194-911X,1524-4563

DOI: 10.1161/hypertensionaha.107.100255